M. Pomothy, Judit and F. Barna, Réka and Szóládi, Áron and Pásztiné-Gere, Erzsébet (2019) The beneficial effects of rosmarinic acid on a non-tumorigenic epithelial cell line. GRADUS, 7 (1). pp. 79-83. ISSN 2064-8014
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Abstract
The aim of this study was to investigate the effects of rosmarinic acid (RA) on a porcine, non-tumorigenic IPEC-J2 enterocyte cell line. The cell viability was tested with MTS assay and the transepithelial electrical resistance (TER) values were measured to determine the changes of the membrane integrity. The extracellular H2O2 production was analyzed with Amplex Red assay. The results show that the RA was not cytotoxic in low concentrations up to 100 uM. At 50 uM concentration RA promoted cell proliferation and did not cause significant increase in H2O2 production.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | IPEC-J2 cell line, Rosmarinic acid, Cell viability, Transepithelial electrical, resistance, Extracellular H2O2 |
| Subjects: | S Agriculture / mezőgazdaság > SB Plant culture / növénytermesztés |
| Depositing User: | Zoltán Subecz |
| Date Deposited: | 08 Jun 2020 13:00 |
| Last Modified: | 28 Apr 2021 15:35 |
| URI: | http://real.mtak.hu/id/eprint/109347 |
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