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Standardization procedure for flow cytometry data harmonization in prospective multicenter studies

Le Lann, Lucas and Alarcón-Riquelme, Marta and Jouve, Pierre-Emmanuel and Balog, Attila and Bocskai, Márta and Deák, Magdolna and Dulic, Sonja and Kádár, Gabriella and Kovács, László (2020) Standardization procedure for flow cytometry data harmonization in prospective multicenter studies. SCIENTIFIC REPORTS, 10 (1). ISSN 2045-2322

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Abstract

One of the most challenging objective for clinical cytometry in prospective multicenter immunomonitoring trials is to compare frequencies, absolute numbers of leukocyte populations and further the mean fluorescence intensities of cell markers, especially when the data are generated from different instruments. Here, we describe an innovative standardization workflow to compare all data to carry out any large-scale, prospective multicentric flow cytometry analysis whatever the duration, the number or type of instruments required for the realization of such projects.

Item Type: Article
Subjects: R Medicine / orvostudomány > RC Internal medicine / belgyógyászat
SWORD Depositor: MTMT SWORD
Depositing User: MTMT SWORD
Date Deposited: 24 Sep 2020 11:22
Last Modified: 24 Sep 2020 11:22
URI: http://real.mtak.hu/id/eprint/114405

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