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Elevated serum purine levels in schizophrenia: a reverse translational study to identify novel inflammatory biomarkers

Kristóf, Zsüliet and Baranyi, Mária and Tod, Pál and Mut-Arbona, Paula and Demeter, Kornél and Bitter, István and Sperlágh, Beáta (2022) Elevated serum purine levels in schizophrenia: a reverse translational study to identify novel inflammatory biomarkers. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2022. ISSN 1461-1457

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Abstract

Immunological markers and related signaling molecules in the blood are altered in schizophrenia mouse models, in acutely relapsed patients with schizophrenia, and in persons at a clinically high risk for subsequently developing psychosis, highlighting their potential as prognostic and theranostic biomarkers. Therefore, we herein aimed to identify novel potential biomarkers in the serum that are associated with purinergic signaling.

Item Type: Article
Uncontrolled Keywords: Biomarkers, neuroinflammation, purinergic signaling, P2X7 receptor, schizophrenia
Subjects: R Medicine / orvostudomány > RA Public aspects of medicine / orvostudomány társadalmi szerepe
R Medicine / orvostudomány > RC Internal medicine / belgyógyászat > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry / idegkórtan, neurológia, pszichiátria
SWORD Depositor: MTMT SWORD
Depositing User: MTMT SWORD
Date Deposited: 01 Jun 2022 13:30
Last Modified: 01 Jun 2022 13:30
URI: http://real.mtak.hu/id/eprint/143225

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