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Seroprevalence of SARS-CoV-2 antibodies among primary healthcare workers in the Republic of Srpska, Bosnia & Herzegovina: A cross-sectional study

Knezevic, Darija and Petkovic, Miroslav and Bozic, Ljiljana and Miljus, Natasa and Mijovic, Biljana and Acimovic, Jela and Djakovic-Devic, Jelena and Puhalo-Sladoje, Dragana and Masic, Srdjan and Spaic, Dragan and Todorovic, Nevena and Pilipovic-Broceta, Natasa and Petrovic, Verica and Bokonjic, Dejan and Stojiljkovic, Milos P. and Skrbic, Ranko (2022) Seroprevalence of SARS-CoV-2 antibodies among primary healthcare workers in the Republic of Srpska, Bosnia & Herzegovina: A cross-sectional study. ACTA MICROBIOLOGICA ET IMMUNOLOGICA HUNGARICA, 69 (1). pp. 18-26. ISSN 1217-8950

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Abstract

Healthcare workers (HCW) in primary healthcare centres in the Republic of Srpska, Bosnia and Herzegovina, are on the first combat line with COVID-19. This study aimed to assess the seroprevalence of SARS-CoV-2 among HCW at the primary healthcare centres and to analyse the risk exposure to COVID-19, clinical signs and vaccination status. A cross-sectional study was conducted among HCW at the selected primary healthcare centres between 19 March and 30 April 2021. Antibodies against the SARS-CoV-2 virus were detected by enzyme-linked immunosorbent assay (ELISA). A total of 1,023 HCW (mean age 45 years; 71% female) were included in the study. The anti-SARS-CoV-2 antibodies were detected in 69.5% of all participants. There was a significant difference in seropositivity among primary healthcare centres from different geographical regions. As many as 432 (42%) of all participants had confirmed COVID-19 symptoms before the study and, 84.8% of them were seropositive. This study showed that 702 primary HCW were vaccinated with any of these vaccines: Sputnik V, Sinopharm, Pfizer/Biontech. High titre of SARS-CoV-2 antibodies was found amongst those who received one (92.6%) or both (97.2%) doses of vaccines. In this study, we report high prevalence of SARS-CoV-2 antibody among HCW in primary healthcare in the Republic of Srpska, Bosnia and Herzegovina during the third pandemic wave.

Item Type: Article
Additional Information: Funding Agency and Grant Number: Ministry of Health and Social Welfare of the Government of the Republic of Srpska; WHO Country office for Bosnia and Herzegovina [202604001] Funding text: The study was co-funded by the Ministry of Health and Social Welfare of the Government of the Republic of Srpska and the WHO Country office for Bosnia and Herzegovina (WHO Purchase order No. 202604001).
Uncontrolled Keywords: immunology; seroprevalence; healthcare workers; COVID-19; SARS-CoV-2;
Subjects: Q Science / természettudomány > QR Microbiology / mikrobiológia
SWORD Depositor: MTMT SWORD
Depositing User: MTMT SWORD
Date Deposited: 25 Jul 2022 08:12
Last Modified: 25 Jul 2022 08:12
URI: http://real.mtak.hu/id/eprint/145141

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