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Why current quantitative serology is not quantitative and how systems immunology could provide solutions

Prechl, József (2021) Why current quantitative serology is not quantitative and how systems immunology could provide solutions. Biologia Futura, 72 (1). pp. 37-44. ISSN 2676-8615 (print), 2676-8607 (online)

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Abstract

Determination of the presence of antibodies against infectious agents, self-antigens, allogeneic antigens and environmental antigens is the goal of medical serology. Along with the standardization of these tests the community also started to use the expression “quantitative serology,” referring to the fact that arbitrary units are used for the expression of results. In this review I will argue against the use of the term quantitative serology for current tests. Because each test and each antibody isotype determination uses its own references, the term semiquantitative better describes these methods. The introduction of really quantitative serology could both benefit from and drive forward systems immunological approach to immunity.

Item Type: Article
Subjects: Q Science / természettudomány > Q1 Science (General) / természettudomány általában
Q Science / természettudomány > QH Natural history / természetrajz > QH301 Biology / biológia
Depositing User: Zsolt Baráth
Date Deposited: 13 Oct 2022 12:50
Last Modified: 13 Oct 2022 13:09
URI: http://real.mtak.hu/id/eprint/151615

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