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Late bedtime is associated with decreased hippocampal volume in young healthy subjects

Kuperczkó, Diána and Perlaki, Gábor and Faludi, Béla and Orsi, Gergely and Altbäcker, Anna and Kovács, Norbert and Dóczi, Tamás Péter and Komoly, Sámuel and Schwarcz, Attila and Clemens, Zsófia and Janszky, József Vladimír (2015) Late bedtime is associated with decreased hippocampal volume in young healthy subjects. SLEEP AND BIOLOGICAL RHYTHMS, 13 (1). pp. 68-75. ISSN 1446-9235

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Abstract

Hippocampal volume loss has been described in several pathological conditions including sleep disorders. Whether differences in normal sleep are associated with differences in hippocampal volume is unknown. Here we designed a study to assess volume of the hippocampus with regard to bedtime, wake up time and sleep duration in 90 healthy university students. To assess hippocampal volumes we applied semi-automatic user-independent magnetic resonance volumetry. We found a significant association between delayed bedtime and smaller hippocampal volumes, a non-significant tendency for smaller hippocampal volumes in the late wake up time group and significantly smaller hippocampal volumes for both short and long sleepers. These results suggest the importance of adequate sleep timing and especially bedtime in determining hippocampal volume.

Item Type: Article
Uncontrolled Keywords: slow wave sleep; sleep; sleep duration; HIPPOCAMPUS; bedtime
Subjects: R Medicine / orvostudomány > RC Internal medicine / belgyógyászat > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry / idegkórtan, neurológia, pszichiátria
SWORD Depositor: MTMT SWORD
Depositing User: MTMT SWORD
Date Deposited: 13 Sep 2015 17:25
Last Modified: 13 Sep 2015 17:25
URI: http://real.mtak.hu/id/eprint/26536

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