REAL

Efficient direct 2,2,2-trifluoroethylation of indoles via C-H functionalization

Tolnai, Gergely László and Székely, A. and Makó, Z. and Gáti, T. and Daru, János and Bihari, Tamás and Stirling, András and Novák, Zoltán (2015) Efficient direct 2,2,2-trifluoroethylation of indoles via C-H functionalization. CHEMICAL COMMUNICATIONS, 51 (21). pp. 4488-4491. ISSN 1359-7345

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Abstract

A novel highly C3 selective metal free trifluoroethylation of indoles using 2,2,2-trifuoroethyl(mesityl)-iodonium triflate was developed. The methodology enables the introduction of a trifluoroethyl group in a fast and efficient reaction under mild conditions with high functional group tolerance. Beyond the synthetic developments, quantum chemical calculations provide a deeper understanding of the transformation. This journal is

Item Type: Article
Subjects: Q Science / természettudomány > QD Chemistry / kémia
SWORD Depositor: MTMT SWORD
Depositing User: MTMT SWORD
Date Deposited: 16 Sep 2015 12:50
Last Modified: 16 Sep 2015 12:50
URI: http://real.mtak.hu/id/eprint/26751

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