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PMAP, PMAPS - DNA PHYSICAL MAP CONSTRUCTING PROGRAMS

Polner, Gábor and Dorgai, László and Orosz, László (1984) PMAP, PMAPS - DNA PHYSICAL MAP CONSTRUCTING PROGRAMS. Nucleic Acids Research, 12 (1). pp. 227-236. ISSN 0305-1048 (print), 1362-4962 (online)

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Abstract

Computer programs are described, which facilitate the construction of the restriction site (physical) map of DNA molecules. By knowing the length of each fragment and its degree of error in the single and the double restriction enzyme digestions, the programs give all the possibilities for the physical map. This method is applicable to linear DNA molecules. Several examples are presented which indicate the high efficiency of the programs in constructing restriction site maps for the 62 Kb chromosome of bacteriophage 16-3. We have constructed complex maps (i.e. EcoRI map with 16 and EqcRV with 11 fragments).

Item Type: Article
Subjects: Q Science / természettudomány > QH Natural history / természetrajz > QH426 Genetics / genetika, örökléstan
Depositing User: Erika Bilicsi
Date Deposited: 13 Nov 2012 07:24
Last Modified: 13 Nov 2012 07:24
URI: http://real.mtak.hu/id/eprint/3341

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