Isolation and structural determination of new metabolites from Artemisia asiatica roots

Zana, Annamária and Hajdú, Zsuzsanna and Jedlinszki, Nikoletta and Máthé, Imre and Dombi, György and Hohmann, Judit (2015) Isolation and structural determination of new metabolites from Artemisia asiatica roots. Tetrahedron, 71 (29). pp. 4817-4820. ISSN 0040-4020

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Abstract Two new 2,2-dimethyl-chromene derivatives and the new pentaisovaleryl sucrose were isolated from the roots of Artemisia asiatica together with the known 1-(5-acetyl-2,4-dihydroxy-phenyl)-3-methyl-butan-1-one, 6-hydroxytremetone and (E)-coniferyl aldehyde. The structures of the compounds were elucidated by extensive 1D (1H, 13C and JMOD) and 2D (1H–1H COSY, HSQC, HMBC and NOESY) NMR studies and APCIMS and HRESIMS investigations. 6-Acetyl-3,7-dihydroxy-2,2-dimethyl-chromene and 6-acetyl-3-hydroxy-2,2-dimethyl-chromene are biogenetically related to 1-(5-acetyl-2,4-dihydroxy-phenyl)-3-methyl-butan-1-one and 6-hydroxytremetone as all having isoprenoid acetophenone origin. All the isolated compounds were described for the first time from this species; interestingly none of them are related to the metabolites identified from the extracts of the aerial part of the plant.

Item Type: Article
Uncontrolled Keywords: Sucrose polyester; Chromene; Acetophenone; ASTERACEAE; Artemisia asiatica
Subjects: Q Science / természettudomány > QH Natural history / természetrajz > QH540 Ecology / ökológia
Q Science / természettudomány > QK Botany / növénytan > QK10 Plant physiology / növényélettan
Depositing User: MTMT SWORD
Date Deposited: 02 May 2016 14:47
Last Modified: 02 May 2016 14:47

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