REAL

A simple integrative electrophysiological model of bursting GnRH neurons

Csercsik, Dávid and Farkas, Imre and Hrabovszky, Erik and Liposits, Zsolt (2012) A simple integrative electrophysiological model of bursting GnRH neurons. JOURNAL OF COMPUTATIONAL NEUROSCIENCE, 32 (1). pp. 119-136. ISSN 0929-5313

[img]
Preview
Text
JCNS962_R2.pdf

Download (828kB) | Preview

Abstract

In this paper a modular model of the GnRH neuron is presented. For the aim of simplicity, the currents corresponding to fast time scales and action potential generation are described by an impulsive system, while the slower currents and calcium dynamics are described by usual ordinary differential equations (ODEs). The model is able to reproduce the depolarizing afterpotentials, afterhyperpolarization, periodic bursting behavior and the corresponding calcium transients observed in the case of GnRH neurons.

Item Type: Article
Subjects: R Medicine / orvostudomány > RC Internal medicine / belgyógyászat > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry / idegkórtan, neurológia, pszichiátria
SWORD Depositor: MTMT SWORD
Depositing User: MTMT SWORD
Date Deposited: 04 May 2016 09:20
Last Modified: 04 May 2016 09:20
URI: http://real.mtak.hu/id/eprint/35119

Actions (login required)

Edit Item Edit Item