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Acute and sub-acute toxicity evaluation of Enterococcus faecalis HZNU P2 isolated from peacock faeces in vivo

Zhang, Y. and Zheng, W. and Ying, Q.C. and Shi, L.-E. and Zhang, Z.-L. and Shi, M.-Z. and Tang, Z.-X. (2016) Acute and sub-acute toxicity evaluation of Enterococcus faecalis HZNU P2 isolated from peacock faeces in vivo. Acta Alimentaria, 45 (4). pp. 477-485. ISSN 0139-3006

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Abstract

The sub-acute toxicity of E. faecalis HZNU P2 was investigated in rats fed with different doses for 14 days. To evaluate the acute oral toxicity of E. faecalis HZNU P2, rats were fed with E. faecalis HZNU P2 at a high dose of 2×10<sup>11</sup> CFU kg<sup>−1</sup> for 10 days. Results showed that there were no abnormal clinical signs in any of the groups during the experiment. There were no significant differences in live weight gain among rats fed with E. faecalis HZNU P2, compared to those in control group. Macroscopic or microscopic examinations of organs revealed no abnormalities, indicating that E. faecalis HZNU P2 did not adversely affect the health of rats. Results of this study demonstrated that digestion of E. faecalis HZNU P2 in rats did not show any obvious signs of toxicity.

Item Type: Article
Subjects: Q Science / természettudomány > QD Chemistry / kémia > QD01 Analytical chemistry / analitikai kémia
Depositing User: Erika Bilicsi
Date Deposited: 05 Dec 2016 10:36
Last Modified: 31 Dec 2017 00:17
URI: http://real.mtak.hu/id/eprint/42826

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