Slow Delayed Rectifier Potassium Current (IKs) and the Repolarization Reserve

Jost, Norbert and Papp, Julius Gyula and Varró, András (2007) Slow Delayed Rectifier Potassium Current (IKs) and the Repolarization Reserve. Annals of Noninvasive Electrocardiology, 12 (1). pp. 64-78. ISSN 1082-720X (print), 1542-474X (online)

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The aim of this review is to present the properties of the slow component of the delayed rectifier potassium current (I-Ks) in the human ventricle. The review gives a detailed description of the physiology, molecular biology and pharmacology of the I-Ks current, including kinetic properties, genetic structures, agonists and antagonists. The authors also present the role of the I-Ks current in the human cardiac repolarization focusing on several pathophysiological situations, such as the LQT syndrome and the Torsade de Pointes arrhythmia.

Item Type: Article
Subjects: R Medicine / orvostudomány > RZ Other systems of medicine / orvostudomány egyéb területei
Depositing User: Erika Bilicsi
Date Deposited: 12 Mar 2013 12:13
Last Modified: 12 Mar 2013 12:13

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