Jost, Norbert and Papp, Julius Gyula and Varró, András (2007) Slow Delayed Rectifier Potassium Current (IKs) and the Repolarization Reserve. Annals of Noninvasive Electrocardiology, 12 (1). pp. 64-78. ISSN 1082-720X (print), 1542-474X (online)
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Abstract
The aim of this review is to present the properties of the slow component of the delayed rectifier potassium current (I-Ks) in the human ventricle. The review gives a detailed description of the physiology, molecular biology and pharmacology of the I-Ks current, including kinetic properties, genetic structures, agonists and antagonists. The authors also present the role of the I-Ks current in the human cardiac repolarization focusing on several pathophysiological situations, such as the LQT syndrome and the Torsade de Pointes arrhythmia.
| Item Type: | Article |
|---|---|
| Subjects: | R Medicine / orvostudomány > RZ Other systems of medicine / orvostudomány egyéb területei |
| Depositing User: | Erika Bilicsi |
| Date Deposited: | 12 Mar 2013 12:13 |
| Last Modified: | 12 Mar 2013 12:13 |
| URI: | http://real.mtak.hu/id/eprint/4391 |
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