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Feed exposure to FB1 can aggravate pneumonic damages in pigs provoked by P. multocida

Kovács, Melinda and Pósa, Roland and Tuboly, Tamás and Donkó, Tamás and Repa, Imre and Tossenberger, János and Szabó-Fodor, Judit and Stoev, Stoycho and Magyar, Tibor (2016) Feed exposure to FB1 can aggravate pneumonic damages in pigs provoked by P. multocida. RESEARCH IN VETERINARY SCIENCE, 108. pp. 38-46. ISSN 0034-5288

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Abstract

The possible interaction between Pasteurella multocida and the mycotoxin fumonisin B1 (FB1), recognised as one of the most often food/feed contaminant, was studied with the aim to evaluate whether and how FB1 can in fl u- ence and/or complicate the development and severity of various pathological damages provoked by Pasteurella multocida in some internal organs of pigs. Heavier lung pathology was seen in pigs experimentally infected with Pasteurella multocida , when the same were exposed to 20 ppm dietary levels of fumonisin B 1 (FB 1 )aswas assessed by gross pathology, pathomorphological examinations, clinical biochemistry and some immunological investigations. The most typical damages in FB 1 treated pigs were the strong oedema in the lung and the slight oedema in the other internal organs and mild degenerative changes in the kidneys, whereas the typical pathomorphological fi ndings in pigs infected with Pasteurella multocida was broncho-interstitial pneumonia. FB1 was found to aggravate pneumonic changes provoked by P. multocida in the cranial lobes of the lung and to complicate pneumonic damages with interstitial oedema in the lung. No macroscopic damages were observed in the pigs infected only with Pasteurella multocida. It can be concluded that the feed intake of FB1 in pigs may complicate or exacerbate the course of P. multocida serotype A infection.

Item Type: Article
Subjects: S Agriculture / mezőgazdaság > SV Veterinary science / állatorvostudomány
Depositing User: Diszterhöft Zoltán
Date Deposited: 07 Feb 2017 11:17
Last Modified: 04 Apr 2023 12:15
URI: http://real.mtak.hu/id/eprint/47578

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