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Field efficacy of combination vaccines against bovine respiratory pathogens in calves

Makoschey, Birgit and Muñoz Bielsa, Juan and Oliviero, Loïc and Roy, Olivier and Pillet, Florence and Dufe, Divine and Valla, Giorgio and Cavirani, Sandro (2008) Field efficacy of combination vaccines against bovine respiratory pathogens in calves. Acta Veterinaria Hungarica, 56 (4). pp. 485-493. ISSN 0236-6290

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Abstract

The efficacy of an inactivated bovine respiratory syncytial virus (BRSV) — bovine parainfluenza type 3 (PI3) — Mannheimia haemolytica ( Mh ) combination vaccine was examined in two field studies. Calves were vaccinated (i) with the inactivated vaccine, (ii) a modified live/killed viral combination vaccine, or (iii) left unvaccinated. The efficacy of the vaccines was judged by the (i) number of treated animals, (ii) number of individual antibiotic treatments per calf and (iii) mortality rates. After vaccination with the inactivated vaccine, the number of calves requiring antibiotic treatment was significantly lower than in the unvaccinated group (odds ratios: 0.26 first study and 0.53 second study), but differences between vaccination with live/killed combination vaccines and controls were not significant (odds ratios: 0.56 and 0.90, respectively). In both studies, a number of unvaccinated controls died due to respiratory disease (4.6% first and 6.7% second study). By contrast, none of the animals vaccinated with the inactivated vaccine died in the first study and only 3.3% in the second study. The mortality rates for the groups vaccinated with the live vaccine (1.3% and 7.8%) were similar to the unvaccinated controls. In summary, these data demonstrate the efficacy of the inactivated vaccine under field conditions.

Item Type: Article
Subjects: S Agriculture / mezőgazdaság > SV Veterinary science / állatorvostudomány
Depositing User: xKatalin xBarta
Date Deposited: 13 Feb 2017 13:34
Last Modified: 13 Feb 2017 13:34
URI: http://real.mtak.hu/id/eprint/48450

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