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Canine tumour suppressor gene p53 mutation in a case of anaplastic carcinoma of the intestine

Mayr, B. and Reifinger, M. (2002) Canine tumour suppressor gene p53 mutation in a case of anaplastic carcinoma of the intestine. Acta Veterinaria Hungarica, 50 (1). pp. 31-35. ISSN 0236-6290

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Abstract

Tumours localised in the large bowel of dogs were subjected to molecular genetic studies. Highly conserved regions of the tumour suppressor gene p53, including typical tumour hot spots (codons 175, 245, 248, 249, 273 and 282), were analysed. A mutation CGG - TGG (arginine - tryptophan) was present in codon 249 in an anaplastic carcinoma in the caecum.

Item Type: Article
Subjects: S Agriculture / mezőgazdaság > SV Veterinary science / állatorvostudomány
Depositing User: xKatalin xBarta
Date Deposited: 16 Feb 2017 13:58
Last Modified: 31 Mar 2022 23:15
URI: http://real.mtak.hu/id/eprint/49275

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