Furusawa, N. (2000) Hepatic biotransformation profiles of sulphamonomethoxine in food-producing animals and rats in vitro. Acta Veterinaria Hungarica, 48 (3). pp. 293-300. ISSN 0236-6290
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Abstract
Hydroxylation and acetylation of sulphamonomethoxine (SMM) and deacetylation of N4-acetyl SMM (N4-AcSMM) were estimated in liver post-mitochondrial supernatants (S-9) from laying hens, female cattle, swine and rats. The formation of hydroxylated SMM, 2,6-dihydroxy SMM (2,6-diOH-SMM), was found only with hen S-9s. N4-acetylation rate of SMM was the highest in pig S-9s, followed by rat, then hen or cow S-9s. All S-9s from the four species deacetylated N4-AcSMM. In hen S-9s, the rate of 2,6-dihydroxylation was higher during incubation at 41 °C than at 37 °C.
| Item Type: | Article |
|---|---|
| Subjects: | S Agriculture / mezőgazdaság > SV Veterinary science / állatorvostudomány |
| Depositing User: | xKatalin xBarta |
| Date Deposited: | 20 Feb 2017 11:56 |
| Last Modified: | 31 Jul 2020 23:15 |
| URI: | http://real.mtak.hu/id/eprint/49479 |
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