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Development of controlled-release devices for photodynamic therapy of cancer

Varga, Stefan and Patachia, Silvia and Ion, Rodica (2007) Development of controlled-release devices for photodynamic therapy of cancer. Pollack Periodica, 2 (2). pp. 131-140. ISSN 1788-1994

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Abstract

Poly (vinyl alcohol) (PVA) is a biocompatible and non-toxic polymer able to form a hydrogel network suitable for drug encapsulation and delivery. A directional controlled release device for porphyrins used in cancer therapy has been devised and implemented based on the swelling and collapse capability of the PVA-based hydrogel. An improved version of this device, having a multi-laminar design with a retarder membrane, is accomplished. The devices can function as model systems for the advanced engineering of transdermal drug-delivery devices for various therapeutic applications (photodynamic therapy, viral inactivation and treatment of psoriasis).

Item Type: Article
Subjects: T Technology / alkalmazott, műszaki tudományok > TA Engineering (General). Civil engineering (General) / általános mérnöki tudományok
Depositing User: Erika Bilicsi
Date Deposited: 18 Oct 2017 15:26
Last Modified: 18 Oct 2017 15:26
URI: http://real.mtak.hu/id/eprint/65674

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