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A straightforward synthesis of indazolo[3,2-a]isoquinolin-6-amines

Balog, József and Riedl, Zsuzsanna and Hajós, György (2013) A straightforward synthesis of indazolo[3,2-a]isoquinolin-6-amines. TETRAHEDRON LETTERS, 54 (39). pp. 5338-5340. ISSN 0040-4039

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Abstract

4-Substituted 1-bromoisoquinolin-3-amines were subjected to Suzuki coupling with o-nitrophenylboronic acid to yield 1-(2-nitrophenyl) isoquinolinamines, which participated in Cadogan cyclization with triethyl phosphite under microwave irradiation in a sealed vial to yield fluorescent indazolo[3,2-a] isoquinolin-6-amines. The new compounds were also functionalized by transformation of the amino group. © 2013 Elsevier Ltd. All rights reserved.

Item Type: Article
Uncontrolled Keywords: synthesis; SUZUKI REACTION; MICROWAVE IRRADIATION; ARTICLE; isoquinoline derivative; Suzuki coupling; nitrene; INDAZOLE; FLUORESCENCE; CYCLIZATION
Subjects: Q Science / természettudomány > QD Chemistry / kémia
SWORD Depositor: MTMT SWORD
Depositing User: MTMT SWORD
Date Deposited: 04 Oct 2013 09:14
Last Modified: 07 Oct 2013 06:56
URI: http://real.mtak.hu/id/eprint/6836

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