REAL

Thyrotropin (TSH) regulates triiodothyronine (T3) production in the unicellular Tetrahymena

Csaba, G. and Pállinger, Éva (2011) Thyrotropin (TSH) regulates triiodothyronine (T3) production in the unicellular Tetrahymena. Acta Biologica Hungarica, 62 (3). pp. 228-234. ISSN 0236-5383

[img] Text
abiol.62.2011.3.2.pdf
Restricted to Repository staff only until 30 September 2031.

Download (145kB)

Abstract

The aim of the experiments was to study the regulation of triiodothyronine (T3) production in the unicellular Tetrahymena. Untreated and troph-hormone treated specimen were prepared and in different timepoints T3 content was measured and compared by immunocytochemical flow cytometry. 0.1 or 0.001 IU TSH in tryptone-yeast medium stimulated T3 synthesis at 10, 20, 30 min, but does not stimulate after 1 h. The overlapping gonadotropic hormone (GTH) also did it, however only at 10 min. In Losina salt solution (physiological for Tetrahymena) the effect was weaker, however outer amino acid source was not absolutely needed for the production of the hormone. The results show that the TSH regulation of thyroid hormone synthesis (storage, secretion) and troph-hormone overlap can be deduced to a unicellular level. This may allow the hypothesis that the endocrine mechanisms proved at a low level of phylogeny are preserved for the higher ranked organisms.

Item Type: Article
Subjects: Q Science / természettudomány > QH Natural history / természetrajz
Depositing User: Endre Sarvay
Date Deposited: 23 Nov 2017 16:32
Last Modified: 23 Nov 2017 16:32
URI: http://real.mtak.hu/id/eprint/70455

Actions (login required)

Edit Item Edit Item