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Key role of lipids in heat stress management

Balogh, Gábor and Péter, Mária and Glatz, Attila and Gombos, Imre and Török, Zsolt and Horváth, Ibolya and Vígh, László (2013) Key role of lipids in heat stress management. FEBS LETTERS, 587 (13). pp. 1970-1980. ISSN 0014-5793

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Abstract

Heat stress is a common and, therefore, an important environmental impact on cells and organisms. While much attention has been paid to severe heat stress, moderate temperature elevations are also important. Here we discuss temperature sensing and how responses to heat stress are not necessarily dependent on denatured proteins. Indeed, it is clear that membrane lipids have a pivotal function. Details of membrane lipid changes and the associated production of signalling metabolites are described and suggestions made as to how the interconnected signalling network could be modified for helpful intervention in disease. (C) 2013 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

Item Type: Article
Uncontrolled Keywords: Molecular Chaperones; CYTOCHROME-C; ARACHIDONIC-ACID; OXIDATIVE STRESS; ESCHERICHIA-COLI; Cellular networks; PLASMA-MEMBRANE; SACCHAROMYCES-CEREVISIAE; SHOCK TRANSCRIPTION FACTOR; THERMOSENSOR CONTROLS EXPRESSION; Signalling network; Membrane sensor; Temperature sensing; membrane lipid; Mild heat exposure; Heat stress
Subjects: Q Science / természettudomány > QH Natural history / természetrajz > QH301 Biology / biológia > QH3011 Biochemistry / biokémia
SWORD Depositor: MTMT SWORD
Depositing User: MTMT SWORD
Date Deposited: 29 Oct 2013 09:01
Last Modified: 29 Oct 2013 10:10
URI: http://real.mtak.hu/id/eprint/7052

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