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Smallest lectin-like peptide identified from the skin secretion of an endemic frog, Hydrophylax bahuvistara

Vineethkumar, Thundiparampil Vasanth and Shyla, Gopal and George, Sanil (2018) Smallest lectin-like peptide identified from the skin secretion of an endemic frog, Hydrophylax bahuvistara. Acta Biologica Hungarica, 69 (1). pp. 110-113. ISSN 0236-5383

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Abstract

Lectins are sugar-binding proteins and considered as attractive candidates for drug delivery and targeting. Here, we report the identification of the smallest lectin-like peptide (odorranalectin HYba) from the skin secretion of Hydrophylax bahuvistara which is being the shortest lectin-like peptide identified so far from the frog skin secretion, with 15 amino acid residues. The peptide is the first report from an Indian frog and lacks antimicrobial activity but strongly agglutinate intact human erythrocytes. The sequences at the L-fucose recognizing region is conserved as in other lectins reported from frog skin secretion and could be exploited for specificity and drug targeting properties.

Item Type: Article
Subjects: Q Science / természettudomány > QH Natural history / természetrajz
Depositing User: Ágnes Sallai
Date Deposited: 06 Apr 2018 08:11
Last Modified: 31 Mar 2019 00:16
URI: http://real.mtak.hu/id/eprint/79036

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