Ujvári, Barbara and Makrai, László and Magyar, Tibor (2018) Characterisation of a multiresistant Pasteurella multocida strain isolated from cattle. Acta Veterinaria Hungarica, 66 (1). pp. 12-19. ISSN 0236-6290
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Abstract
The emergence of simultaneous resistance to multiple classes of antibiotics presents an increasing threat. Plasmid-borne multiresistance and integrative conjugative elements have been reported in Pasteurella multocida. We report an alternative strategy for the development of multiresistance observed in a P. multocida strain (Pm238) isolated from calf pneumonia. We identified genes integrated into the chromosomal DNA without known integrative and conjugative elements. These genes conferred resistance to streptomycin (strA), tetracycline (tetB), chloramphenicol (catAIII), and sulphonamides (sulII). We also detected mutation in the quinolone-resistance-determining regions of parC. No plasmids could be isolated from strain Pm238. These results suggest that P. multocida can accumulate multiple resistance determinants on the chromosome as single genes.
| Item Type: | Article |
|---|---|
| Additional Information: | MTA KFB támogatási szerződés alapján archiválva |
| Subjects: | S Agriculture / mezőgazdaság > SV Veterinary science / állatorvostudomány |
| Depositing User: | Violetta Baliga |
| Date Deposited: | 11 Apr 2018 14:07 |
| Last Modified: | 31 Mar 2019 00:16 |
| URI: | http://real.mtak.hu/id/eprint/79121 |
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