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Potential markers of the atherosclerotic process in high-risk children

Szamosi, Tamás and Mihai, K. and Pető, Judit and Makary, A. and Kramer, Judit (1991) Potential markers of the atherosclerotic process in high-risk children. CLINICAL BIOCHEMISTRY, 24 (2). pp. 185-187. ISSN 0009-9120

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Abstract

Children whose parents had early coronary heart disease were investigated. In order to assess high-risk parameters serum total cholesterol (TC), total triglyceride (TT), high-density lipoprotein cholesterol (HDLC), low-density lipoprotein cholesterol (LDLC), lipid peroxide (LP), prostacyclin (PGI2), thromboxane (TX) levels, and the distribution of the complement 3 (C3), protein phenotypes were measured. Compared to a group of control children, the offspring of high-risk subjects had increased LDLC, LP, TC, and TX levels, a higher incidence of fast-slow heterozygotes, and decreased HDLC and PGI2 levels. The measurement of serum PGI2, TX levels and the distribution of C3 protein phenotypes may give further information about the true risk of atherosclerosis.

Item Type: Article
Uncontrolled Keywords: Triglycerides/blood; Thromboxanes/blood; Risk Factors; PHENOTYPE; Male; Lipoproteins, HDL/blood; Lipid Peroxides/blood; Humans; Female; Epoprostenol/blood; Coronary Disease/diagnosis; Complement C3/metabolism; Cholesterol, LDL/blood; Cholesterol/blood; Child, Preschool; Child; Biological Markers; Arteriosclerosis/*diagnosis/metabolism; Adolescent
Subjects: Q Science / természettudomány > QH Natural history / természetrajz > QH301 Biology / biológia > QH3011 Biochemistry / biokémia
Q Science / természettudomány > QH Natural history / természetrajz > QH426 Genetics / genetika, örökléstan
SWORD Depositor: MTMT SWORD
Depositing User: MTMT SWORD
Date Deposited: 14 Sep 2018 17:05
Last Modified: 14 Sep 2018 17:05
URI: http://real.mtak.hu/id/eprint/84073

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