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A novel passerivirus (family Picornaviridae) in an outbreak of enteritis with high mortality in estrildid finches (Uraeginthus sp.)

Pankovics, Péter and Boros, Ákos and Phan, Gia Tung and Delwart, Eric (2018) A novel passerivirus (family Picornaviridae) in an outbreak of enteritis with high mortality in estrildid finches (Uraeginthus sp.). Archives of Virology, 163 (4). pp. 1063-1071. ISSN 0304-8608

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Abstract

An enteric outbreak with high mortality (34/52, 65.4%) was recorded in 2014 in home-reared estrildid finches (Estrildidae) in Hungary. A novel passerivirus was identified in a diseased violet-eared waxbill using viral metagenomics and confirmed by RT-(q)PCR. The complete genome of finch picornavirus strain waxbill/DB01/HUN/2014 (MF977321) showed the highest amino acid sequence identity of 38.9%, 61.6%, 69.6% in P1cap, 2Chel and 3CproDpol, respectively, to passerivirus A1 (GU182406). A high viral load (6.58 × 1010 genomic copies/ml) was measured in a cloacal specimen and in the tissues (spinal cord, lung, and the intestines) of two additional affected finches. In addition to intestinal symptoms (diarrhoea), the presence of extra-intestinal virus suggests a generalized infection in this fatal disease, for which the passerivirus might be a causative agent.

Item Type: Article
Subjects: Q Science / természettudomány > QR Microbiology / mikrobiológia > QR355 Virology / víruskutatás
Depositing User: Dr. Peter Pankovics
Date Deposited: 18 Sep 2018 07:31
Last Modified: 05 Apr 2023 07:41
URI: http://real.mtak.hu/id/eprint/84261

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