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Synthesis of α-aminophosphonates by the Kabachnik–Fields reaction and by the Pudovik reaction

Bálint, Erika and Tripolszky, Anna and Tajti, Ádám (2018) Synthesis of α-aminophosphonates by the Kabachnik–Fields reaction and by the Pudovik reaction. In: Organophosphorus Chemistry - Novel Developments. Walter de Gruyter GmbH, Berlin, pp. 108-147. ISBN 978-3-11-053583-9

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Abstract

α-Aminophosphonates are of significant importance due to their biological activity. The most widely applied synthetic routes towards α-aminophosphonates are the Kabachnik-Fields reaction involving the condensation of amines, oxo compounds and >P(O)H species, such as dialkyl phosphites, and the Pudovik reaction of imines and >P(O)H reagents. By the double Kabachnik-Fields reaction, bis(aminophosphonates) have also became available. This chapter summarizes the synthesis of α-aminophosphonates and related derivatives through the two main routes as described in the literature over the last five years.

Item Type: Book Section
Subjects: Q Science / természettudomány > Q1 Science (General) / természettudomány általában
Q Science / természettudomány > QD Chemistry / kémia
Q Science / természettudomány > QD Chemistry / kémia > QD04 Organic chemistry / szerves kémia
Depositing User: Dr. Erika Bálint
Date Deposited: 29 Sep 2018 15:28
Last Modified: 29 Sep 2018 15:28
URI: http://real.mtak.hu/id/eprint/86013

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