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Electrospun nanofibers for entrapment of biomolecules

Balogh Weiser, Diána and Németh, Csaba and Ender, Ferenc and Gyarmati, Benjámin Sándor and Szilágyi, András Ferenc and Poppe, László (2018) Electrospun nanofibers for entrapment of biomolecules. In: Electrospinning Method Used to Create Functional Nanocomposites Films. InTech Open Access Publisher, Rijeka, pp. 135-147. ISBN 978-1-78923-581-4

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Abstract

This chapter focuses on nanoiber fabrication by electrospinning techniques for the efective immobilization of biomolecules (such as enzymes or active pharmaceutical ingredients—APIs). In this chapter, the development of precursor materials (from commercial polymer systems to systematically designed biopolymers), entrapment protocols, and precursor-nanoiber characterization methods are represented. The entrapment ability of poly(vinyl alcohol) and systematically modiied polyaspartamide nanoibers was investigated for immobilization of two diferent lipases (from Candida antarctica and Pseudomonas luorescens) and for formulation of the antibacterial and antiviral agent, rifampicin. The encapsulated biomolecules in electrospun polymer ibers could be promising nanomaterials for industrial biocatalysis to produce chiral compound or in the development of smart drug delivery systems.

Item Type: Book Section
Subjects: Q Science / természettudomány > QD Chemistry / kémia
SWORD Depositor: MTMT SWORD
Depositing User: MTMT SWORD
Date Deposited: 30 Sep 2018 08:59
Last Modified: 30 Sep 2018 08:59
URI: http://real.mtak.hu/id/eprint/86073

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