Complete genome sequence of C130_2, a novel myovirus infecting pathogenic Escherichia coli and Shigella strains

Sváb, Domonkos and Falgenhauer, Linda and Rohde, Manfred and Chakraborty, Trinad and Tóth, István (2019) Complete genome sequence of C130_2, a novel myovirus infecting pathogenic Escherichia coli and Shigella strains. ARCHIVES OF VIROLOGY, 164 (1). pp. 321-324. ISSN 0304-8608

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Abstract

The genome sequence of a novel virulent bacteriophage, named “ C130_2”, that is morphologically a member of the family Myoviridae is reported. The 41,775-base-pair double-stranded DNA genome of C130_2 contains 59 ORFs but exhibits overall low sequence similarity to bacteriophage genomes for which sequences are publicly available. Phylogenetic analysis indicated that C130_2 represents a new phage type. C130_2 could be propagated well on enterohemorrhagic Escherichia coli (EHEC) O157:H7 and other pathogenic E. coli strains, as well as on strains of various Shigella species.

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