Items where Author is "Ligeti, Zoltán"

Article

Huszár, Krisztina and Welker, Zsombor and Györgypál, Zoltán and Tóth, Eszter and Ligeti, Zoltán and Kulcsár, Péter István and Dancsó, János and Tálas, András and Krausz, Sarah Laura and Varga, Éva and Welker, Ervin (2023) Position-Dependent Sequence Motif Preferences of SpCas9 are Largely Determined by Scaffold-Complementary Spacer Motifs. NUCLEIC ACIDS RESEARCH, 51 (11). pp. 5847-5863. ISSN 0305-1048 (print); 1362-4962 (online)

Kulcsár, Péter István and Tálas, András and Ligeti, Zoltán and Tóth, Eszter and Rakvács, Zsófia and Bartos, Zsuzsa and Krausz, Sarah Laura and Welker, Ágnes and Végi, Vanessza Laura and Huszár, Krisztina and Welker, Ervin (2023) A cleavage rule for selection of increased-fidelity SpCas9 variants with high efficiency and no detectable off-targets. NATURE COMMUNICATIONS, 14 (1). No.-5746. ISSN 2041-1723

Kulcsár, Péter István and Tálas, András and Ligeti, Zoltán and Krausz, Sarah Laura and Welker, Ervin (2022) SuperFi-Cas9 Exhibits Remarkable Fidelity But Severely Reduced Activity Yet Works Effectively with ABE8e. NATURE COMMUNICATIONS, 13. pp. 1-11. ISSN 2041-1723

Kulcsár, Péter István and Tálas, András and Tóth, Eszter and Nyeste, Antal and Ligeti, Zoltán and Welker, Zsombor and Welker, Ervin (2020) Blackjack mutations improve the on-target activities of increased fidelity variants of SpCas9 with 5′G-extended sgRNAs. NATURE COMMUNICATIONS, 11. pp. 1-14. ISSN 2041-1723

Tóth, Eszter and Varga, Éva and Kulcsár, Péter István and Kocsis-Jutka, Virág and Krausz, Sarah Laura and Nyeste, Antal and Welker, Zsombor and Huszár, Krisztina and Ligeti, Zoltán and Tálas, András and Welker, Ervin (2020) Improved LbCas12a variants with altered PAM specificities further broaden the genome targeting range of Cas12a nucleases. Nucleic Acids Research. pp. 1-12. ISSN 0305-1048 (print); 1362-4962 (online)

Tóth, Eszter and Czene, Bernadett C and Kulcsár, Péter István and Krausz, Sarah and Tálas, András and Nyeste, Antal and Varga, Éva and Huszár, Krisztina and Weinhardt, Nóra and Ligeti, Zoltán and Borsy, Adrienn Éva and Ayaydin-Fodor, Elfrieda and Welker, Ervin (2018) Mb- and FnCpf1 nucleases are active in mammalian cells. NUCLEIC ACIDS RESEARCH, 46 (19). pp. 10272-10285. ISSN 0305-1048

Kulcsár, Péter István and Tálas, András and Huszár, Krisztina and Ligeti, Zoltán and Tóth, Eszter and Weinhardt, Nóra and Ayaydin-Fodor, Elfrieda and Welker, Ervin (2017) Crossing enhanced and high fidelity SpCas9 nucleases to optimize specificity and cleavage. GENOME BIOLOGY, 18. p. 190. ISSN 1474-7596

Tálas, András and Kulcsár, Péter István and Weinhardt, Nóra and Borsy, Adrienn and Tóth, Eszter and Szebényi, Kornélia and Krausz, Sarah Laura and Huszár, Krisztina and Vida, István and Sturm, Ádám and Gordos, Bianka and Hoffmann, Orsolya Ivett and Bencsura, Petra and Nyeste, Antal and Ligeti, Zoltán and Fodor, Elfrieda and Welker, Ervin (2017) A convenient method to pre-screen candidate guide RNAs for CRISPR/Cas9 gene editing by NHEJ-mediated integration of a 'self-cleaving' GFP-expression plasmid. DNA RESEARCH, 24 (6). pp. 609-621. ISSN 1340-2838