Non-Coding RNAs in Adrenocortical Cancer: From Pathogenesis to Diagnosis.

Decmann, Ábel and Perge, Pál and Turai, Peter István and Patócs, Attila and Igaz, Péter (2020) Non-Coding RNAs in Adrenocortical Cancer: From Pathogenesis to Diagnosis. CANCERS, 12 (2). ISSN 2072-6694


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Non-coding RNA molecules including microRNAs and long non-coding RNAs (lncRNA) have been implicated in the pathogenesis of several tumors and numerous data support their applicability in diagnosis as well. Despite recent advances, the pathogenesis of adrenocortical cancer still remains elusive and there are no reliable blood-borne markers of adrenocortical malignancy, either. Several findings show the potential applicability of microRNAs as biomarkers of malignancy and prognosis, and there are some data on lncRNA as well. In this review, we present a synopsis on the potential relevance of non-coding RNA molecules in adrenocortical pathogenesis and their applicability in diagnosis from tissue and blood.

Item Type: Article
Additional Information: Journal Article; Review
Uncontrolled Keywords: microRNA; biomarker; LncRNA; Adrenocortical cancer; Non-coding RNA;
Subjects: R Medicine / orvostudomány > RC Internal medicine / belgyógyászat > RC0254 Neoplasms. Tumors. Oncology (including Cancer) / daganatok, tumorok, onkológia
Depositing User: MTMT SWORD
Date Deposited: 24 Feb 2020 10:47
Last Modified: 24 Feb 2020 10:47

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