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Attachment of Primary Mouse Astroglial Cells on Neural Implant Surfaces

Bérces, Zsófia and Csernyus, Bence and Liliom, Hanna Laura and Schlett, Katalin and Pinke, D. and Lőw, Péter and Horváth, Ágoston Csaba and Fekete, Zoltán and Pongrácz, Anita (2016) Attachment of Primary Mouse Astroglial Cells on Neural Implant Surfaces. PROCEDIA ENGINEERING, 168. pp. 172-175. ISSN 1877-7058

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Abstract

In vitro micro- and nanofabricated test chips were used to investigate mouse primary cortical astroglial cell reactions to different surfaces of a multichannel neural microelectrode implant. The following surface types were fabricated by MEMS technology and characterized by scanning electron microscopy: poly-Si, Pt, nanostructured Si and nanostructured Pt. Survival of primary cortical mouse astroglial cells was analysed by fluorescent microscopy 24 hours after seeding. Our results show that the nanostructured surfaces are not toxic to the primary mouse astroglial cells.

Item Type: Article
Uncontrolled Keywords: gliosis; BCI; cell-surface interaction; neural implant; NeuroMEMS; primary astroglial cells;
Subjects: R Medicine / orvostudomány > R1 Medicine (General) / orvostudomány általában > R850-854 Experimental medicine / kisérleti orvostudomány
R Medicine / orvostudomány > RC Internal medicine / belgyógyászat > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry / idegkórtan, neurológia, pszichiátria
SWORD Depositor: MTMT SWORD
Depositing User: MTMT SWORD
Date Deposited: 04 Jan 2021 14:51
Last Modified: 04 Jan 2021 14:51
URI: http://real.mtak.hu/id/eprint/119038

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