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The diverse functional roles and regulation of neuronal gap junctions in the retina.

Bloomfield, S. A. and Völgyi, Béla (2009) The diverse functional roles and regulation of neuronal gap junctions in the retina. NATURE REVIEWS NEUROSCIENCE, 10 (7). pp. 459-506. ISSN 1471-003X

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Abstract

Electrical synaptic transmission through gap junctions underlies direct and rapid neuronal communication in the CNS. The diversity of functional roles that electrical synapses have is perhaps best exemplified in the vertebrate retina, in which gap junctions are formed by each of the five major neuron types. These junctions are dynamically regulated by ambient illumination and by circadian rhythms acting through light-activated neuromodulators such as dopamine and nitric oxide, which in turn activate intracellular signalling pathways in the retina.The networks formed by electrically coupled neurons are plastic and reconfigurable, and those in the retina are positioned to play key and diverse parts in the transmission and processing of visual information at every retinal level.

Item Type: Article
Subjects: R Medicine / orvostudomány > RC Internal medicine / belgyógyászat > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry / idegkórtan, neurológia, pszichiátria
R Medicine / orvostudomány > RE Ophthalmology / szemészet
SWORD Depositor: MTMT SWORD
Depositing User: MTMT SWORD
Date Deposited: 05 Aug 2014 06:35
Last Modified: 05 Aug 2014 11:26
URI: http://real.mtak.hu/id/eprint/14072

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