Szabó, Zoltán and Hornyák, Lilla and Miskei, Márton and Székvölgyi, Lóránt (2021) Two Targets , One Hit : new Anticancer Therapeutics to Prevent Tumorigenesis Without Cardiotoxicity. FRONTIERS IN PHARMACOLOGY, 11. p. 569955. ISSN 1663-9812
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Abstract
A serious adverse effect of cancer therapies is cardiovascular toxicity, which significantly limits the widespread use of antineoplastic agents. The promising new field of cardio-oncology offers the identification of potent anti-cancer therapeutics that effectively inhibit cancer cell proliferation without causing cardiotoxicity. Future introduction of recently identified cardio-safe compounds into clinical practice (including ERK dimerization inhibitors or BAX allosteric inhibitors) is expected to help oncologists avoid unwanted cardiological complications associated with therapeutic interventions.
| Item Type: | Article |
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| Subjects: | Q Science / természettudomány > Q1 Science (General) / természettudomány általában R Medicine / orvostudomány > R1 Medicine (General) / orvostudomány általában > R850-854 Experimental medicine / kisérleti orvostudomány R Medicine / orvostudomány > RC Internal medicine / belgyógyászat > RC0254 Neoplasms. Tumors. Oncology (including Cancer) / daganatok, tumorok, onkológia |
| Depositing User: | Dr Lóránt Székvölgyi |
| Date Deposited: | 12 Sep 2022 12:18 |
| Last Modified: | 03 Apr 2023 07:58 |
| URI: | http://real.mtak.hu/id/eprint/148397 |
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