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Synthesis of new spin labels for Cu-free click conjugation

Kálai, Tamás and Flessner, Mark R. and Jekö, József and Hubbell, W. L. and Hideg, Kálmán (2011) Synthesis of new spin labels for Cu-free click conjugation. TETRAHEDRON LETTERS, 52. pp. 2747-2749. ISSN 0040-4039

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Abstract

New pyrroline nitroxides attached to a terminal acetylenic sulfone, a dibenzocyclooctyne or a cyclooctyne carboxylic acid were synthesized and tested in Cu-free click reactions to conjugate these new spin labels with 4-azido-TEMPO, azidophenylalanine and an azidophenylalanine-containing protein.

Item Type: Article
Subjects: Q Science / természettudomány > QD Chemistry / kémia > QD04 Organic chemistry / szerves kémia
Depositing User: Dr. Tamás Kálai
Date Deposited: 09 Jan 2015 11:16
Last Modified: 09 Jan 2015 11:16
URI: http://real.mtak.hu/id/eprint/20178

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