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Efficient Copper-Catalyzed Trifluoromethylation of Aromatic and Heteroaromatic Iodides: The Beneficial Anchoring Effect of Borates

Gonda, Zsombor and Kovács, Szabolcs and Wéber, Csaba and Gáti, Tamás and Mészáros, Attila and Kotschy, András and Novák, Zoltán (2014) Efficient Copper-Catalyzed Trifluoromethylation of Aromatic and Heteroaromatic Iodides: The Beneficial Anchoring Effect of Borates. Organic Letters, 16. pp. 4268-4271. ISSN 1523-7060

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Abstract

Efficient copper - catalyzed trifluoromethylation of aromatic iodides was achieved with TMSCF 3 in the presence of trimethoxyborane. The Lewis acid was used to anchor the in situ generated trifluoromethyl anion and suppress its rapid decomp os i- tion. Broad applicability of the new trifluoromethylating reaction was demonstrated in the functionali zation of different aromatic and heteroaro matic iodides.

Item Type: Article
Subjects: Q Science / természettudomány > QD Chemistry / kémia > QD04 Organic chemistry / szerves kémia
Depositing User: Dr. Zoltán Novák
Date Deposited: 10 Feb 2015 13:16
Last Modified: 10 Feb 2015 13:16
URI: http://real.mtak.hu/id/eprint/21501

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