REAL

TRPV3 : a 'more than skinny' channel

Nilius, Bernd and Bíró, Tamás (2013) TRPV3 : a 'more than skinny' channel. EXPERIMENTAL DERMATOLOGY, 22 (7). pp. 447-452. ISSN 0906-6705

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Abstract

The skin is our largest organ serving different tasks from barrier formation through somatosensing to hair development. Recently, members of the large trp (Transient Receptor Potential, TRP) gene family encoding proteins that form cation selective ion channel have been identified to play a crucial role in skin functions. Within the 28 different mammalian TRP channels, TRPV3 might be the most important member in the skin. This review gives an overview on functional properties of TRPV3 in skin physiology and in certain skin diseases. © 2013 John Wiley & Sons A/S.

Item Type: Article
Uncontrolled Keywords: Tissue Survival; tissue growth; skin pain; skin disease; review; PATHOPHYSIOLOGY; Olmsted syndrome; nonhuman; human; hair growth; gene mutation; functions of the skin and its appendages; drug effect; dermatitis; VANILLOID RECEPTOR ANTAGONIST; vanilloid receptor 3 antagonist; vanilloid receptor 3; VANILLOID RECEPTOR; unclassified drug; Transient receptor potential vanilloid-3; Skin diseases; PROLIFERATION; Keratinocyte; DIFFERENTIATION
Subjects: Q Science / természettudomány > QH Natural history / természetrajz > QH301 Biology / biológia > QH3015 Molecular biology / molekuláris biológia
R Medicine / orvostudomány > R1 Medicine (General) / orvostudomány általában
SWORD Depositor: MTMT SWORD
Depositing User: MTMT SWORD
Date Deposited: 13 Feb 2015 14:53
Last Modified: 13 Feb 2015 14:53
URI: http://real.mtak.hu/id/eprint/21740

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