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Novel stereocontrolled syntheses of tashiromine and epitashiromine

Kiss, Lorand and Forró, Enikő and Fülöp, Ferenc (2015) Novel stereocontrolled syntheses of tashiromine and epitashiromine. Beilstein Journal of Organic Chemistry, 11. pp. 596-603. ISSN - ; ESSN: 1860-5397

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Abstract

A novel stereocontrolled approach has been developed for the syntheses of tashiromine and epitashiromine alkaloids from cyclooctene β-amino acids. The synthetic concept is based on the azetidinone opening of a bicyclic β-lactam, followed by oxidative ring opening through ring C–C double bond and reductive ring-closure reactions of the cis- or trans-cyclooctene β-amino acids.

Item Type: Article
Subjects: Q Science / természettudomány > QD Chemistry / kémia > QD04 Organic chemistry / szerves kémia
Depositing User: Dr Loránd Kiss
Date Deposited: 11 Sep 2015 07:28
Last Modified: 11 Sep 2015 07:30
URI: http://real.mtak.hu/id/eprint/26340

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