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High Prevalence and Resistance Patterns of Community-Associated Methicillin-Resistant Staphylococcus aureus in the Pomoravlje Region, Serbia

Lepsanovic, Zorica and Jeremic, Ljiljana Petrovic and Lazic, Srdjan and Cirkovic, Ivana (2016) High Prevalence and Resistance Patterns of Community-Associated Methicillin-Resistant Staphylococcus aureus in the Pomoravlje Region, Serbia. Acta Microbiologica et Immunologica Hungarica, 63 (1). pp. 83-92. ISSN 1217-8950

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Abstract

With a view to estimating the prevalence and resistance patterns of CA-MRSA in one region of Serbia, we performed an analysis of MRSA isolates from healthy people and hospitalised patients. The detection of CA-MRSA was carried out by SCCmec typing. In MRSA isolates from hospitalised patients SCCmec types IV and V were found in 76% of the strains. Similar percentage (80%) of CA-MRSA genotypes was present in healthy people. SCCmec type V harbouring MRSA was the most successful clone. Higher prevalence of type V in hospitalised patients to that in healthy people (70% vs 54%) may indicate nosocomial transmissions in at least some hospital units. All MRSA strains from hospitalised patients were resistant to one or more non-β-lactam antibiotics while 52% were multi-resistant. In isolates from healthy people, 16% were sensitive to all non-β-lactam antibiotics and 40% were multi-resistant. Similar percentage of multi-resistant CA- and HA-genotypes occurred in a particular environment (53% vs 50% in hospitalised patients, and 37.5% vs 37.5% in healthy people) indicating selective pressure of antibiotics as a leading force conferring antibiotic resistance. High prevalence of CA-MRSA and high resistance rate both in hospitals and the community suggest that this pathogen has been present in the Pomoravlje Region, central Serbia for years.

Item Type: Article
Subjects: Q Science / természettudomány > QR Microbiology / mikrobiológia
Depositing User: Ágnes Sallai
Date Deposited: 08 Jun 2016 07:56
Last Modified: 31 Mar 2017 23:15
URI: http://real.mtak.hu/id/eprint/35648

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