Characterisation of Hungarian porcine circovirus 2 genomes associated with PMWS and PDNS cases

Dán, Á. and Molnár, T. and Biksi, I. and Glávits, R. and Shaheim, M. and Harrach, B. (2003) Characterisation of Hungarian porcine circovirus 2 genomes associated with PMWS and PDNS cases. Acta Veterinaria Hungarica, 51 (4). pp. 551-562. ISSN 0236-6290

Preview

Text avet.51.2003.4.13.pdf Download (253kB) | Preview

Abstract

The authors report the data of the first survey on the incidence of postweaning multisystemic wasting syndrome (PMWS) and porcine dermatitis and nephropathy syndrome (PDNS) in Hungary. A PCR method specific for the detection of porcine circovirus 2 (PCV-2) was developed, which proved to be suitable for diagnostic purposes. PCR screening of organ samples from pigs suspected to be affected with PMWS or PDNS revealed the presence of PCV-2 in 80% of the cases. Six PCV-2 genomes from Hungarian isolates were completely sequenced. Phylogenetic comparison with all the available PCV-2 sequences showed that porcine circoviruses circulating in Hungary are more variable than in several other European countries. Two Hungarian strains clustered together with the Spanish strains forming a distinct group; two others fell in a common group with the French, UK, and Dutch strains, whereas another two strains showed the closest relationship to two of the three known German PCV-2 sequences.

Actions (login required)

Edit Item