Optimization of triacetylfusarinine C and ferricrocin productions in Aspergillus fumigatus

Szigeti, Zsuzsa and Szaniszló, Szilvia and Fazekas, Erika and Gyémánt, Gyöngyi and Szabon, Judit and Antal, Károly and Emri, Tamás and Balla, József and Balla, György and Csernoch, László and Pócsi, István (2014) Optimization of triacetylfusarinine C and ferricrocin productions in Aspergillus fumigatus. Acta Microbiologica et Immunologica Hungarica, 61 (2). pp. 107-119. ISSN 1217-8950

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Iron is an essential element for all microorganisms. Bacteria and fungi produce versatile siderophores for binding and storing this essential transition metal when its availability is limited in the environment. The aim of the study was to optimize the fermentation medium of Aspergillus fumigatus for siderophore production. Triacetyl-fusarinine C and ferricrocin yields were dependent on glucose and glycine supplementations as well as the initial pH of the culture media. The optimal fermentation medium for triacetylfusarinine C production contained 8% glucose, 0.4% glycine and the initial pH was set to 5.9. Meanwhile, maximal ferricrocin yields were recorded in the presence of 10% glucose, 0.5% glycine and at an initial pH of 7.4. Under optimized fermentation conditions, the yields for triacetylfusarinine C and ferricrocin increased up to 2.9 g/l culture medium and 18.9 mg/g mycelium, respectively.

Item Type: Article
Subjects: Q Science / természettudomány > QR Microbiology / mikrobiológia
Depositing User: Ágnes Sallai
Date Deposited: 28 Mar 2017 07:47
Last Modified: 28 Mar 2017 07:47

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