Candida bloodstream infection: A clinical microbiology laboratory perspective

Pongrácz, Júlia and Kristóf, Katalin (2014) Candida bloodstream infection: A clinical microbiology laboratory perspective. Acta Microbiologica et Immunologica Hungarica, 61 (3). pp. 389-398. ISSN 1217-8950

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The incidence of Candida bloodstream infection (BSI) has been on the rise in several countries worldwide. Species distribution is changing; an increase in the percentage of non-albicans species, mainly fluconazole non-susceptible C. glabrata was reported. Existing microbiology diagnostic methods lack sensitivity, and new methods need to be developed or further evaluation for routine application is necessary. Although reliable, standardized methods for antifungal susceptibility testing are available, the determination of clinical breakpoints remains challenging. Correct species identification is important and provides information on the intrinsic susceptibility profile of the isolate. Currently, acquired resistance in clinical Candida isolates is rare, but reports indicate that it could be an issue in the future. The role of the clinical microbiology laboratory is to isolate and correctly identify the infective agent and provide relevant and reliable susceptibility data as soon as possible to guide antifungal therapy.

Item Type: Article
Subjects: Q Science / természettudomány > QR Microbiology / mikrobiológia
Depositing User: Ágnes Sallai
Date Deposited: 28 Mar 2017 12:11
Last Modified: 28 Mar 2017 12:11

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