Signal transduction in fungi - the role of protein phosphorylation

Szirák, Krisztina and Fehér, Z. (1999) Signal transduction in fungi - the role of protein phosphorylation. Acta Microbiologica et Immunologica Hungarica, 46 (2-3). pp. 269-271. ISSN 1217-8950


Download (109kB) | Preview


Living cells are able to respond to the surrounding environment. As a first step in this process, membrane receptors react with an extracellular ligand. There are three main families of cell-surface receptors: (1) Ion-channel-linked receptors, (2) G-protein-linked receptors, and (3) Enzyme-linked receptors that either act directly as enzymes or are associated with enzymes. These enzymes are oftenprotein kinasesthat phosphorylate specific proteins in the target cell. Through cascades of phosphorylations elaborate sets of proteins relay signals from the receptor to the nucleus regulating gene expression. There are two groups of protein kinases: tyrosine- and serine-threonine-specific protein kinases and there areprotein phosphataseswith specificity for the appropriate side chain to match each type of kinase. They can terminate an activation event reversing the phosphorylation caused by a protein kinase.

Item Type: Article
Subjects: Q Science / természettudomány > QR Microbiology / mikrobiológia
Depositing User: xFruzsina xPataki
Date Deposited: 10 Sep 2017 10:57
Last Modified: 31 May 2019 23:15

Actions (login required)

Edit Item Edit Item