Sexual and enteric bacterial infections eliciting reactive artritis (A review)

Ongrádi, Joseph (2001) Sexual and enteric bacterial infections eliciting reactive artritis (A review). Acta Microbiologica et Immunologica Hungarica, 48 (3-4). pp. 441-448. ISSN 1217-8950

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In this review synonymous definitions of reactive arthritis are discussed first. Major clinical symptoms, their infectious etiology and epidemiology define post-dysenteric and post-venereal forms of reactive arthritis. Classical (smear, culture, biochemistry, antigen detection) and molecular (DNA and RNA detections) techniques are used in the routine microbial diagnosis that is retrospective in the majority of cases. In the pathomechanism of this disorder, HLA-B27 antigen positivity of patients is a frequent risk factor. Molecular mimicry between microbial and self-antigens, abnormal antigen presentation leading to incomplete CD8+ T lymphocyte activation might contribute to the persistence of microbial antigens that elicit clinical symptoms. Treatment is rarely successful with antimicrobial chemotherapy.

Item Type: Article
Subjects: Q Science / természettudomány > QR Microbiology / mikrobiológia
Depositing User: xFruzsina xPataki
Date Deposited: 11 Sep 2017 06:15
Last Modified: 11 Sep 2017 06:15

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