Virulence Factors and Resistance Mechanisms of Serratia marcescens

Rodrigues, Ana P. and Holanda, A. R. M. and Lustosa, G. P. and Nóbrega, S. M. B. and Santana, Willma J. and Souza, Luciana B. S. and Coutinho, H. D. M. (2006) Virulence Factors and Resistance Mechanisms of Serratia marcescens. Acta Microbiologica et Immunologica Hungarica, 53 (1). pp. 89-93. ISSN 1217-8950

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Abstract

Serratia marcescens, a Gram-negative bacillus that belongs to the family Enterobacteriaceae, is a human opportunistic pathogen bacterium that causes many diseases, such as urinary tract infections, respiratory tract infections, bacteremia, conjunctivitis, endocarditis, meningitis and wound infections. Many plasmides that confers multi-drug resistance were discovered, such as virulence factors, like cytotoxins that damage epithelial cells. The main topic of this paper presents a review about the molecular traits evolved in the pathogenic processes mediated by Serratia and its mechanism of resistance to drugs.

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