Clinical microbiology of neonatal candidiasis in Hungary

Kristóf, Katalin and Janik, L. and Komka, Kinga and Harmath, Ágnes and Hajdú, Júlia and Nobilis, A. and Rozgonyi, F. and Nagy, K. and Rigó, J. JR. and Szabó, Dóra (2010) Clinical microbiology of neonatal candidiasis in Hungary. Acta Microbiologica et Immunologica Hungarica, 57 (4). pp. 407-417. ISSN 1217-8950

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The occurrence of Candida spp. was investigated during a three-year period in two neonatal intensive care units, Budapest, Hungary. The species distribution among the 41 analysed cases was the following: C. albicans (30/41, 73%), C. parapsilosis (10/41, 24%) and C. glabrata (1/41, 3%). All of the isolates were susceptible to the tested drugs. There was a significant difference in the birth weight, the gestational age <30 weeks and the occurrence of caesarean section between the C. albicans and the C. parapsilosis groups of the cases. Respiratory tract colonization was the same (76–77%) in the extremely low birth weight (ELBW) and the very low birth weight (VLBW) groups. Comparing the ELBW, VLBW, and >1500 g birth weight groups, significant difference was found in the parenteral nutrition, the gestation weeks <36 or <30, the polymicrobial infection and the transfusion. The ratio of C. albicans, C. parapsilosis and C. glabrata was 9:7:1 in ELBW group; 6:3:0 in VLBW group and 15:1:0 in >1500 g group. The mortality rate for C. parapsilosis was higher than for C. albicans.

Item Type: Article
Subjects: Q Science / természettudomány > QR Microbiology / mikrobiológia
Depositing User: xFruzsina xPataki
Date Deposited: 17 Sep 2017 18:49
Last Modified: 17 Sep 2017 18:49

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