Liver abscess as the presenting manifestation of chronic granulomatous disease

Mamishi, Setareh and Ahmadi, Faezeh and Ahmadi, Maedeh and Rezaei, Nima (2011) Liver abscess as the presenting manifestation of chronic granulomatous disease. Acta Microbiologica et Immunologica Hungarica, 58 (4). pp. 297-301. ISSN 1217-8950

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Abstract

Chronic granulomatous disease (CGD) is a rare primary immunodeficiency disease, affecting phagocytic blood cells, which predispose patients to recurrent infectious complications. Herein, an 11-year-old girl is described who presented with liver abscess at the age of 9 years. Positive dihydrorhodamine (DHR) and nitrobluetetrazolium (NBT) tests confirmed the diagnosis of CGD for the patient. Anti-tuberculosis drugs and parenteral antibiotic therapy were started. Unusual visceral abscess and recurrent infections should be considered as an alarm for primary immunodeficiency diseases, while early diagnosis and appropriate treatment could prevent severe complications and even death in this group of patients.

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