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Induction of programmed cell death in aging Prorocentrum donghaiense cells as was evidenced preliminarily by the identification of associated transcripts

Zhang, Xiufang and Yang, G. and Liu, Y. and Yu, W. and Pan, K. and Li, Ruixiang and Zhu, M. (2006) Induction of programmed cell death in aging Prorocentrum donghaiense cells as was evidenced preliminarily by the identification of associated transcripts. Acta Biologica Hungarica, 57 (4). pp. 473-483. ISSN 0236-5383

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Abstract

Prorocentrum donghaiense caused large-scale red tides off Chinese coast in recent years. Expressed sequence tag (EST) analysis was carried out for this dinoflagellate in order to identify the genes involved in its proliferation and death. A cDNA library was constructed for P. donghaiense at late exponential growth phase, and 308 groups of EST were generated, which include 36 contigs and 272 singletons. Among 22 groups showed homologies with known genes, 2 matched significantly with caspase and proliferating cell nuclear antigen. Caspase and proliferating cell nuclear antigen are 2 key proteins involved in programmed cell death. Their identification evidenced preliminarily the induction of PCD in aging P. donghaiense. The identified included also calmodulin and protein phosphatase, two proteins involved in diverse cell processes including PCD by binding to or modifying others.

Item Type: Article
Subjects: Q Science / természettudomány > QH Natural history / természetrajz
Depositing User: Endre Sarvay
Date Deposited: 20 Nov 2017 14:40
Last Modified: 20 Nov 2017 14:40
URI: http://real.mtak.hu/id/eprint/70101

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