REAL

Genes encoding cuticular proteins are components of the Nimrod gene cluster in Drosophila.

Cinege, Gyöngyi Ilona and Zsámboki, János and Vidal-Quadras, M. and Uv, Anne and Csordás, Gábor and Honti, Viktor and Gábor, Erika and Hegedűs, Zoltán and Varga, Gergely István and Juhász, Gábor and Andó, István and Kurucz, Judit Éva (2017) Genes encoding cuticular proteins are components of the Nimrod gene cluster in Drosophila. INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY, 87. pp. 45-54. ISSN 0965-1748

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Abstract

The Nimrod gene cluster, located on the second chromosome of Drosophila melanogaster, is the largest synthenic unit of the Drosophila genome. Nimrod genes show blood cell specific expression and code for phagocytosis receptors that play a major role in fruit fly innate immune functions. We previously identified three homologous genes (vajk-1, vajk-2 and vajk-3) located within the Nimrod cluster, which are unrelated to the Nimrod genes, but are homologous to a fourth gene (vajk-4) located outside the cluster. Here we show that, unlike the Nimrod candidates, the Vajk proteins are expressed in cuticular structures of the late embryo and the late pupa, indicating that they contribute to cuticular barrier functions.

Item Type: Article
Subjects: Q Science / természettudomány > QH Natural history / természetrajz > QH301 Biology / biológia > QH3011 Biochemistry / biokémia
SWORD Depositor: MTMT SWORD
Depositing User: MTMT SWORD
Date Deposited: 23 Jan 2018 09:34
Last Modified: 23 Jan 2018 09:34
URI: http://real.mtak.hu/id/eprint/73034

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