Nuclear membrane stretch and its role in mechanotransduction

Enyedi, Balázs and Niethammer, Philipp (2017) Nuclear membrane stretch and its role in mechanotransduction. NUCLEUS, 8 (2). pp. 156-161. ISSN 1949-1034

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Most research in nuclear mechanotransduction has focused on the nuclear lamina and lamin binding proteins. These structures provide mechanical stability to the nucleus, establish a link between the cytoskeleton and chromatin, and can transmit mechanical signals. At the same time, mechanical perturbations to the nucleus also affect its phospholipid membranes. In this commentary, we discuss how changes in nuclear membrane tension can mediate mechanotransduction. © 2017 Taylor & Francis

Item Type: Article
Uncontrolled Keywords: nuclear envelope; membrane tension; mechanosensing; inflammatory signals; cPL; cell swelling; Cell lysis
Subjects: T Technology / alkalmazott, műszaki tudományok > TK Electrical engineering. Electronics Nuclear engineering / elektrotechnika, elektronika, atomtechnika
Depositing User: MTMT SWORD
Date Deposited: 16 Feb 2018 12:34
Last Modified: 16 Feb 2018 12:34

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