Long-term stability and reusability of molecularly imprinted polymers

Kupai, József and Razali, Mayamin and Buyuktiryaki, Sibel and Kecili, Rustem and Székely, György (2017) Long-term stability and reusability of molecularly imprinted polymers. POLYMER CHEMISTRY, 8 (4). pp. 666-673. ISSN 1759-9962


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Molecularly imprinted materials are man-made mimics of biological receptors. Their polymer network has recognition sites complementary to a substrate in terms of size, shape and chemical functionality. They have diverse applications in various chemical, biomedical and engineering fields such as solid phase extraction, catalysis, drug delivery, pharmaceutical purification, (bio)sensors, water treatment, membrane separations and proteomics. The stability and reusability of molecularly imprinted polymers (IPs) have crucial roles in developing applications that are reliable, economic and sustainable. In the present article the effect of crosslinkers, functional monomers and conditions for template extraction on the long-term stability and reusability of IPs was systematically investigated. Adsorption capacity, selectivity, morphology and thermal decomposition of eleven different l-phenylalanine methyl ester imprinted polymers were studied to reveal performance loss over 100 adsorption-regeneration cycles. Furthermore, crosslinker and functional monomer specific reversible and irreversible decomposition of imprinted polymers as a result of adsorbent regeneration were investigated through adsorption studies, electron microscopy, N2 adsorption and thermogravimetric analysis. A decomposition mechanism was proposed and revealed using NMR spectroscopy. Solutions to avoid or overcome the limitations of the most common crosslinkers, functional monomers and extraction techniques were proposed and experimentally validated. © The Royal Society of Chemistry 2017.

Item Type: Article
Uncontrolled Keywords: POLYMERS; SOLID-PHASE EXTRACTION; molecularly imprinted polymer; Irreversible decomposition; Decomposition Mechanism; Chemical functionality; Adsorption-regeneration cycles; Adsorption capacities; Adsorbent regeneration; water treatment; Thermogravimetric analysis; Reusability; Phase separation; Organic polymers; Nuclear magnetic resonance spectroscopy; MONOMERS; Molecular Biology; EXTRACTION; Biological Materials; amino acids; ADSORPTION
Subjects: Q Science / természettudomány > QD Chemistry / kémia > QD04 Organic chemistry / szerves kémia
Depositing User: MTMT SWORD
Date Deposited: 24 Aug 2018 07:52
Last Modified: 24 Aug 2018 07:52

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