Histology-based simulations of ultrasound imaging : methodology

Gyöngy, Miklós and Balogh, Lajos and Szalai, Klára and Kalló, Imre (2013) Histology-based simulations of ultrasound imaging : methodology. ULTRASOUND IN MEDICINE AND BIOLOGY, 39 (10). pp. 1925-1929. ISSN 0301-5629

[img] Text
Restricted to Repository staff only

Download (1MB) | Request a copy


Simulations of ultrasound (US) images based on histology may shed light on the process by which microscopic tissue features translate to a US image and may enable predictions of feature detectability as a function of US system parameters. This technical note describes how whole-slide hematoxylin and eosin-stained histology images can be used to generate maps of fractional change in bulk modulus, whose convolution with the impulse response of the US system yields simulated US images. The method is illustrated by two canine mastocytoma histology images, one with and the other without signs of intra-operative hemorrhaging. Quantitative comparisons of the envelope statistics with corresponding clinical US images provide preliminary validation of the method.

Item Type: Article
Uncontrolled Keywords: Simulation, Modeling, Histology, Envelope statistics, Tissue microstructure, Ultrasonic tissue characterization.
Subjects: R Medicine / orvostudomány > R1 Medicine (General) / orvostudomány általában
Depositing User: MTMT SWORD
Date Deposited: 08 Jan 2014 14:28
Last Modified: 14 Jan 2014 15:26

Actions (login required)

Edit Item Edit Item